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Leonard S Dove Selected Research

eluxadoline

1/2020Effects of treatment with eluxadoline on abdominal pain in patients with IBS-D: Additional post hoc analyses of Phase 3 trials.
1/2019Impact of patient and disease characteristics on the efficacy and safety of eluxadoline for IBS-D: a subgroup analysis of phase III trials.
1/2018Evaluation of Eluxadoline Effect on Cardiac Repolarization.
7/2017Eluxadoline Demonstrates a Lack of Abuse Potential in Phase 2 and 3 Studies of Patients With Irritable Bowel Syndrome With Diarrhea.
6/2017Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use.
1/2017Safety of Eluxadoline in Patients with Irritable Bowel Syndrome with Diarrhea.
1/2016Eluxadoline for Irritable Bowel Syndrome with Diarrhea.
12/2014Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers.
8/2013Eluxadoline benefits patients with irritable bowel syndrome with diarrhea in a phase 2 study.

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Leonard S Dove Research Topics

Disease

6Abdominal Pain (Pain, Abdominal)
01/2020 - 08/2013
6Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
07/2017 - 08/2013
6Diarrhea
07/2017 - 08/2013
3Nausea
01/2018 - 01/2016
3Constipation
01/2017 - 08/2013
1Gastroesophageal Reflux (GERD)
01/2019
1Dizziness (Lightheadedness)
01/2018
1Contact Dermatitis (Eczema, Contact)
01/2018
1Pancreatitis
01/2017
1Spasm (Spasms)
01/2017
1Nervous System Diseases (Neurological Disorders)
04/2002

Drug/Important Bio-Agent (IBA)

9eluxadolineIBA
01/2020 - 08/2013
4Opioid Receptors (Opioid Receptor)IBA
01/2017 - 08/2013
2Loperamide (Imodium)FDA LinkGeneric
06/2017 - 12/2014
2Opioid Analgesics (Opioids)IBA
01/2017 - 01/2016
2Narcotic Antagonists (Opioid Antagonists)IBA
01/2016 - 08/2013
1Transaminases (Aminotransferases)IBA
01/2017
1Lipase (Acid Lipase)FDA Link
01/2017
1Castor Oil (Oil, Castor)IBA
12/2014
1Calcium Channels (Calcium Channel)IBA
04/2002
1voltage-dependent calcium channel (P-Q type)IBA
04/2002

Therapy/Procedure

1Therapeutics
06/2017